منابع مشابه
RNA granules
Cytoplasmic RNA granules in germ cells (polar and germinal granules), somatic cells (stress granules and processing bodies), and neurons (neuronal granules) have emerged as important players in the posttranscriptional regulation of gene expression. RNA granules contain various ribosomal subunits, translation factors, decay enzymes, helicases, scaffold proteins, and RNA-binding proteins, and the...
متن کاملRNA granules in germ cells.
"Germ granules" are cytoplasmic, nonmembrane-bound organelles unique to germline. Germ granules share components with the P bodies and stress granules of somatic cells, but also contain proteins and RNAs uniquely required for germ cell development. In this review, we focus on recent advances in our understanding of germ granule assembly, dynamics, and function. One hypothesis is that germ granu...
متن کاملPlant RNA Regulatory Network and RNA Granules in Virus Infection
Regulation of post-transcriptional gene expression on mRNA level in eukaryotic cells includes translocation, translation, translational repression, storage, mRNA decay, RNA silencing, and nonsense-mediated decay. These processes are associated with various RNA-binding proteins and cytoplasmic ribonucleoprotein complexes many of which are conserved across eukaryotes. Microscopically visible aggr...
متن کاملRNA binding proteins, microRNAs, and Cytoplasmic RNA granules
Molecular Structure and Function, Research Institute, The Hospital for Sick Children, and 5 Department of Biochemistry & Laboratory Medicine, University of Toronto 6 s 7 8 9 10 Correspondence Address: 11 12 Program in Molecular Structure & Function 13 Research Institute, 14 The Hospital for Sick Children, 15 Atrium 3653; 555 University Avenue, 16 Toronto, Ontario, 17 M5G 1X8 18 Phone: 416-813-8...
متن کاملGRSF1 Regulates RNA Processing in Mitochondrial RNA Granules
Various specialized domains have been described in the cytosol and the nucleus; however, little is known about compartmentalization within the mitochondrial matrix. GRSF1 (G-rich sequence factor 1) is an RNA binding protein that was previously reported to localize in the cytosol. We found that an isoform of GRSF1 accumulates in discrete foci in the mitochondrial matrix. These foci are composed ...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2006
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.200512082